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Year : 2008  |  Volume : 12  |  Issue : 1  |  Page : 29-32

Monitoring of plasma butyrylcholinesterase activity and hematological parameters in pesticide sprayers

1 Epidemiology Section, Industrial Toxicology Research Centre, PB No. 80, Lucknow - 226 001, India
2 Analytical Toxicology Section, Industrial Toxicology Research Centre, PB No. 80, Lucknow - 226 001, India

Correspondence Address:
S K Rastogi
Industrial Toxicology Research Centre, PB No.80, Lucknow - 226 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5278.40813

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To evaluate the health impact of spraying organophosphorus insecticides (OPs), 34 male sprayers in the mango belt of Malihabad, a small town located 27 km from Lucknow in North India was selected. Plasma butyryl cholinesterase (PBChE) and complete blood count were assessed among sprayers after spraying pesticides and the findings obtained were compared with those determined in a reference group ( n = 18). The most common symptoms observed were burning sensation in the eyes (8.82%), itching/skin irritation (23.52%) and chest symptoms (32.35%) in the exposed workers. Plasma butyrylcholinesterase (PBChE) was significantly decreased in workers. The results indicated significant decrease in the mean value of hemoglobin, hematocrit and platelets count; however, significantly higher count of leukocytes was also observed in the exposed group (sprayers) compared to that observed in the control group (P < 0.05). Monitoring of PBChE in pesticide sprayers could be useful to predict and prevent health hazards of OPs.


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