Indian Journal of Occupational and Environmental Medicine   Official publication of Indian Association of  0ccupational  Health  
 Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Users Online:778

  IAOH | Subscription | e-Alerts | Feedback | Login 

Home About us Current Issue Archives Search Instructions
   Next article
   Previous article
   Table of Contents

   Similar in PUBMED
     Search Pubmed for
     Search in Google Scholar for
   Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded407    
    Comments [Add]    
    Cited by others 16    

Recommend this journal


Year : 2008  |  Volume : 12  |  Issue : 3  |  Page : 107-111

Neopterin: Biomarker of cell-mediated immunity and potent usage as biomarker in silicosis and other occupational diseases

National Institute of Miner's Health, JNARDDC Campus, Nagpur, India

Correspondence Address:
Shubhangi K Pingle
Research Officer, National Institute of Miners' Health, JNARDDC Campus, Wadi, Nagpur - 440 023
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5278.44690

Rights and Permissions

Neopterin is regarded as an early biomarker of the cellular immune response. This low molecular mass compound belongs to the class of pteridine and is a metabolite of guanosine triphosphate, which is produced by the activated macrophages and dendritic cells after stimulation with γ-interferon. An international group acknowledges the fact that the levels of serum neopterin can be used as a marker of the effect of exposure to silica and other occupational diseases. The determination of neopterin is an innovative tool for monitoring diseases associated with the activation of cell-mediated immunity.


Print this article     Email this article