Indian Journal of Occupational and Environmental Medicine   Official publication of Indian Association of  0ccupational  Health  
 Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Users Online:693

  IAOH | Subscription | e-Alerts | Feedback | Login 

Home About us Current Issue Archives Search Instructions
   Next article
   Previous article
   Table of Contents

   Similar in PUBMED
     Search Pubmed for
     Search in Google Scholar for
   Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded74    
    Comments [Add]    
    Cited by others 2    

Recommend this journal


Year : 2019  |  Volume : 23  |  Issue : 1  |  Page : 28-31

Blood pressure and lipid profile in automechanics in relation to lead exposure

1 Department of Chemical Pathology, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria
2 Department of Human Biochemistry, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria

Correspondence Address:
Mrs. Chikaodili Nwando Obi-Ezeani
Department of Chemical Pathology, Chukwuemeka Odumegwu Ojukwu University, Awka, Anambra State
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijoem.IJOEM_122_18

Rights and Permissions

Context: Elevated blood pressure and alterations in lipid and lipoproteins play a major role in the development and progression of cardiovascular diseases. Aim: This study is aimed at determining the blood pressure and lipid profile in automechanics. Settings and Design: A total of 120 male subjects between 18 and 55 years of age comprised 60 automechanics and 60 age-matched occupationally unexposed control subjects in Emene, Enugu State, Nigeria. Subjects and Methods: Four milliliters of fasting blood samples was collected from all subjects, 2 mL of blood was dispensed into K2-EDTA vacutainer tube for blood lead analysis, while the other 2 mL was dispensed into plain vacutainer tube, allowed to retract, centrifuged, and the serum used for serum lipid profile analysis. Blood pressure was measured using aneroid sphygmomanometer. Statistical Analysis: Statistical Package for Social Sciences (SPSS) version 21.0 was used for data analysis. Results: Automechanics had significantly higher values of systolic and diastolic blood pressures compared with the controls. Serum levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), and triglyceride (TG) were also significantly higher in the automechanics compared with the controls (P < 0.05); serum high-density lipoprotein cholesterol (HDL-C) level, however, did not differ significantly between the two groups (P > 0.05). Blood lead level showed a significant positive correlation (P < 0.05) with systolic and diastolic blood pressures, serum TC, LDL-C, VLDL-C, and TG, with no significant correlation with serum HDL-C (P > 0.05) in the automechanics and no correlation in the controls. Conclusion: The result of this study indicates that blood pressure is elevated and lipid profile altered in automechanics which suggests that these groups of workers are prone to increased risk of developing hypertension and cardiovascular disorders due to occupational exposure to lead.


Print this article     Email this article