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  Table of Contents 
Year : 2022  |  Volume : 26  |  Issue : 1  |  Page : 33

Persistent organic pollutants and diabetes mellitus: Correspondence

1 Private Academic Consultant, Bangkok, Thailand
2 Honorary Professor, Dr DY Patil University, Pune, Maharshtra, India

Date of Submission26-Nov-2021
Date of Decision10-Dec-2021
Date of Acceptance11-Dec-2021
Date of Web Publication7-Apr-2022

Correspondence Address:
Dr. Pathum Sookaromdee
Private Academic Consultant, Bangkok
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijoem.ijoem_337_21

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How to cite this article:
Sookaromdee P, Wiwanitkit V. Persistent organic pollutants and diabetes mellitus: Correspondence. Indian J Occup Environ Med 2022;26:33

How to cite this URL:
Sookaromdee P, Wiwanitkit V. Persistent organic pollutants and diabetes mellitus: Correspondence. Indian J Occup Environ Med [serial online] 2022 [cited 2023 Mar 28];26:33. Available from:

Dear Editor,

We would like to share ideas on “Persistent organic pollutants—environmental risk factors for diabetes mellitus?—A population-based study.[1]” Ramalingam et al.[1] concluded that “Three OC pesticides and one organophosphate pesticide were strongly associated with increasing blood sugar levels …….” We agree that an environmental chemical hazard might induce problems including diabetes. However, a pathological process should last long and a cross-sectional study can only tell a point association. The pathogenesis is interesting. Whether toxic substances disturb pancreatic endocrine function or induce gluconeogenesis requires further studies. Additionally, blood glucose is a rough estimation. The hexokinase method is an old technique with possible laboratory interference.[2] Examples of interfering substances are hemoglobin and bilirubin.[2] Hemoglobin A1C determination might be a useful parameter to support whether there is a poor nutritional behavior that might be associated with diabetes. Diabetes may be present in a subject who has a poor health behavior or lifestyle, has been exposed to toxic substances, and has poor nutritional practices.

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  References Top

Ramalingam S, Narayanan R, Muthusamy S, Veronika M, Sankaran R, Toscano W. Persistent organic pollutants-environmental risk factors for diabetes mellitus? – A population-based study. Indian J Occup Environ Med 2021;25:157-62.  Back to cited text no. 1
  [Full text]  
Jain R, Myers TF, Kahn SE, Zeller WP. How accurate is glucose analysis in the presence of multiple interfering substances in the neonate? (glucose analysis and interfering substances). J Clin Lab Anal 1996;10:13-6.  Back to cited text no. 2


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